Yichong Zhao / Eric Zhao (赵奕冲) is an AI engineer at Preferred Networks, a Tokyo-based AI unicorn, in its AI Products & Solutions division — where he builds LLM-based agents for operations-research problems and, more broadly, for the kind of complex, open-ended problems found in the real world. He also works on the post-training of nucleic-acid sequence language models within a JST CREST project.

Research interests

  • AI agents — for search, exploration, and open-ended real-world tasks.
  • LLM / VLM post-training & alignment — strengthening meta-skills and agentic capability.
  • Accelerating scientific discovery with LLMs — hypothesis generation, experimentation, and reasoning over the literature.

Experience

2025 — Present

AI Engineer · Preferred Networks, Inc.

AI Products & Solutions · Tokyo, Japan

  • Developing LLM-based agents for solving operations-research problems.
  • Post-training of nucleic-acid sequence language models (JST CREST project).
2023 — 2025

Research Intern → Part-time Engineer · Preferred Networks, Inc.

Tokyo, Japan

2024 — 2025

Early Joiner & Manager · Spark+ Inc.

University of Tokyo (Matsuo Lab)–originated AI startup

  • Led development of the company's flagship SaaS, ORION — an enterprise AI agent that searches and reasons over internal company data (text, charts, diagrams, even handwriting), built for manufacturing knowledge work.
  • Joined at a very early stage and helped establish the foundational organization.
2023

Software Engineer Intern · Recruit Co., Ltd.

Recommender systems & MLOps

2022 — 2023

Software Engineer Intern · Landit Inc.

Web development & web crawling

Education

2023 — 2025

M.S. in Computational Biology & Medical Sciences

University of Tokyo · Graduate School of Frontier Sciences

Advisor: Susumu Goto

  • Research on NLP and text mining for biomedical literature.
2019 — 2023

B.Eng. in Electrical Engineering & Bioscience

Waseda University · School of Advanced Science and Engineering

Advisor: Michiaki Hamada

  • Thesis on language models for nucleic-acid sequences.

Publications & Talks

PLOS ONE
2024

GenerRNA: A Generative Pre-trained Language Model for De Novo RNA Design

Yichong Zhao, Kenta Oono, Hiroki Takizawa, Masaaki Kotera

PLOS ONE, 19(10): e0310814, 2024

The first decoder-only (GPT-2-based) language model trained on RNA sequences. I led the full pipeline — data curation, tokenizer design, pre-training, fine-tuning, and evaluation.

arXiv
2025

Can Frontier LLMs Replace Annotators in Biomedical Text Mining? Analyzing Challenges and Exploring Solutions

Yichong Zhao, Susumu Goto

arXiv preprint, arXiv:2503.03261, 2025

Benchmarked frontier LLMs against BERT-family models on biomedical text mining, analyzing why LLMs underperform and the domain-specific constraints that limit them.

APBJC
2024

Enhancing Biological Text Mining with LLMs: Systematic Prompt Engineering and Data Augmentation

Yichong Zhao, Susumu Goto

Asia-Pacific Bioinformatics Joint Conference (APBJC 2024)

JMAI
2024

Development of an RNA-Generative AI Model via Large-Scale Pre-training (大規模事前学習モデルによるRNA生成AIモデルの開発) JMAI Research Award

Yichong Zhao, Masaaki Kotera

Japanese Association for Medical AI (JMAI 2024)

Selected Projects

2026

Humanoid Hack Tokyo 1st Place

Programmed a Unitree G1 humanoid robot to perform traditional Japanese mochi-pounding (mochitsuki) — awarded 1st place for its completeness and originality at this international physical-AI hackathon.

Humanoid Hack Tokyo — 1st place
2024

GENIAC — 8×7B LLM from scratch

Trained an 8×7B large language model from scratch within Japan's GENIAC initiative (supported by METI), collaborating with a Matsuo Lab team. I was primarily responsible for the model-training phase.

weblab-GENIAC on Hugging Face
2020

Vinterview — AI mock-interview app

Built an AI mock-interview app that won multiple awards at the 100 Program hackathon and drew interest from an incubator.

Honors & Certifications

  • 2024 JMAI Research Award — Japanese Association for Medical AI (oral presentation)
  • 2023 JSBi Certified Bioinformatics Engineer — Japanese Society for Bioinformatics
  • 2022 Applied Information Technology Engineer — Information-technology Promotion Agency, Japan (IPA)